MacCHESS: MX and BioSAXS capabilities

Microcrystallography, high-pressure cryocooling and BioSAXS at MacCHESS

The Macromolecular Diffraction Facility at the Cornell High Energy Synchrotron Source (MacCHESS) is a national research resource supported by the National Center for Research Resources of the US National Institutes of Health. MacCHESS is pursuing several research initiatives designed to benefit both CHESS users and the wider structural biology community. Three initiatives are presented in furth...

MacCHESS Advances: Microcrystallography and More

Microcrystallography Crystals of proteins and other biological macromolecules never grow very big, due to the “soft” nature of the molecules and the weakness of the forces holding them together. At CHESS and other synchrotron sources, it is routine to deal with crystals that are ~100 μm across, but how often do we need to work with even smaller crystals? Ithaca High School student Sarah Kim, un...

Using Flash MX and Flash MX Remoting

What is Flash? Programmers use ActionScript, which is Flash’s programming language, to create these user interfaces. All of Flash’s capabilities discussed above with the use of Flash Remoting help programmers to create responsive client­server Internet applications that enrich the user’s experience. Flash programmers and Flash users now both have an easier time with the creation of Flash MX ...

Mx Mx Example Mx Source Part 1 Mx Source Part 2

NSRL for MX

The cancer potency of MX ("mutagen X"; 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)furanone) was estimated from dose-response data of multiple MX-responding tumor sites observed among male and female rats exposed orally (Komulainen et al., 1997; 2000). These sites were liver, adrenal and thyroid in both sexes and mammary gland in the female. Other sites were associated with treatment, but were j...